Qifuyin against CCL11-Induced cognitive impairment by inhibiting microglial senescence via CCR3 signaling

Qifuyin against CCL11-Induced cognitive impairment by inhibiting microglial senescence via CCR3 signaling

Abstract Background The chemokine CCL11 is negatively correlated with cognitive function and is able to cause dysfunctions of synaptic plasticity. This research investigate whether CCL11 induce microglia senescence to damage synaptic plasticity and the protective role of Qifuyin. Method This study i...

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Bibliographic Details
Main Authors: Sheng Tian, Tianyuan Ye, Chao Tian, Yipeng Zhang, He Li, Hui Shen, Youhua Xu, Xiaorui Cheng
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Immunity & Ageing
Subjects:
CCL11
Qifuyin
Synaptic plasticity
Cellular senescence
Cognitive impairment
Online Access:https://doi.org/10.1186/s12979-025-00528-6
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https://doi.org/10.1186/s12979-025-00528-6

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