Circulating Nucleosomes and Histones in the Development of Lung Injury and Sepsis

Cellular nucleosomes—the structural and functional units of chromatin—are inherently present in cells. During cellular damage or cell death, nucleosomes are released into circulation, either actively or passively. Once released, nucleosomes can become immunogenic entities through various mechanisms....

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Main Authors: Saugata Dutta, Sauradeep Dutta, Payaningal R. Somanath, S. Priya Narayanan, Xiaoyun Wang, Duo Zhang
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Current Issues in Molecular Biology
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Online Access:https://www.mdpi.com/1467-3045/47/2/133
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