A pilot study exploring long-read nanopore metagenomics sequencing for heteroresistance detection in clinical specimens

Introduction: Heteroresistance occurs when most cells in a single bacterial population are susceptible to an antibiotic, while a minority exhibit resistance, and may underpin discrepancies between in vitro susceptibility results and clinical responses. The resistant subpopulation may be present at a...

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Bibliographic Details
Main Authors: Miss Siphiwe Matukane, Miss Khensani Hattingh, Dr Kristien Nel Van Zyl, Dr Mae Newton-Foot, Prof Andrew Whitelaw
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971224004648
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