Exposure to high altitude leads to disturbances in host metabolic homeostasis: study of the effects of hypoxia-reoxygenation and the associations between the microbiome and metabolome

Exposure to high altitude leads to disturbances in host metabolic homeostasis: study of the effects of hypoxia-reoxygenation and the associations between the microbiome and metabolome

ABSTRACT This study investigated alterations in hematological parameters, gut microbiota composition, and fecal and plasma metabolic profiles among high-altitude residents during reoxygenation periods of 1 week, 1 month, and 4 months to elucidate the effects of reoxygenation on human physiology and...

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Bibliographic Details
Main Authors: Qin Zhao, Doudou Hao, Siyu Wang, Siyuan Chen, Chaohua Zhou, Chen Fan, Qian Su, Wenting Huang, Jiaxin Liu, Qingquan Kong, Yunhong Wu, Zeng He
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:mSystems
Subjects:
hypoxia
reoxygenation
plateau population
gut microbiota
metabolism
Online Access:https://journals.asm.org/doi/10.1128/msystems.01347-24
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https://journals.asm.org/doi/10.1128/msystems.01347-24

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