Obinutuzumab combined with bendamustine for the treatment of hairy cell leukemia variant: a case report and literature review

Obinutuzumab combined with bendamustine for the treatment of hairy cell leukemia variant: a case report and literature review

Hairy cell leukemia variant (HCL-v) is a rare and more aggressive subtype of B-cell leukemia. While it shares certain clinical features with classical hairy cell leukemia (HCL-c), HCL-v typically follows a more malignant course and responds poorly to conventional therapies. We report a case of HCL-v...

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Bibliographic Details
Main Authors: Junjun Bai, Yi Zhang, Kangqi Lv, Bei Zhang, Hongxia Wang, Zhixin Pei, Yingxin Zhao, Jingjing Gu, Huimin Wu, Qinglin Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
hairy cell leukemia variant
obinutuzumab
bendamustine
targeted therapy
BRAF wild-type
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1635856/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1635856/full

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