Effects of estrogen inhibition formula herbal mixture for danazol-induced precocious puberty in female rats: An experimental study with network pharmacology

Effects of estrogen inhibition formula herbal mixture for danazol-induced precocious puberty in female rats: An experimental study with network pharmacology

Background: This study aimed at determining the effect of the herbal mixture estrogen inhibition formula (EIF) and its possible mechanisms by precocious puberty animal models and network pharmacology-based analysis. Methods: Precocious puberty animal models were established by a single injection of...

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Bibliographic Details
Main Authors: Seung Chan Park, Tuy An Trinh, Won-Yung Lee, Ji Yun Baek, Seungyong Lee, Kyuhee Choi, Jaewon Ha, Chang-Eop Kim, Ki Sung Kang, Hye Lim Lee
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Integrative Medicine Research
Subjects:
Herbal medicine
Estrogen inhibition
Hypothalamic-pituitary-gonads axis (HPGA)
network pharmacology
Puberty
Online Access:http://www.sciencedirect.com/science/article/pii/S2213422020303450
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