Nucleotide coordinated polymers, a ROS-based immunomodulatory antimicrobial, doubly kill Pseudomonas aeruginosa biofilms of implant infections

Nucleotide coordinated polymers, a ROS-based immunomodulatory antimicrobial, doubly kill Pseudomonas aeruginosa biofilms of implant infections

Pseudomonas aeruginosa causes high morbidity and mortality in nosocomial infections, and newly approved antibiotics have been declining for decades. A green and universal deprotonation-driven strategy is used to screen the guanylic acid-metal ion coordination polymer nanoparticles (GMC), instead of...

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Bibliographic Details
Main Authors: Jinghuang Chen, Xianqing Tang, Qihan Sun, Xin Ji, Xingbo Wang, Zhendong Liu, Xu Zhang, Haijiao Xu, Fan Yang, Jian Sun, Xiurong Yang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-02-01
Series:Bioactive Materials
Subjects:
Nucleotide coordinated polymers
ROS
Immune activation
Sterilization
Pseudomonas aeruginosa biofilm infections
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X24004791
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