Correlation of precisely fabricated geometric characteristics of DNA-origami nanostructures with their cellular entry in human lens epithelial cells
Abstract Human lens epithelial cells (hLECs) are critical for lens transparency, and their aberrant metabolic activity and gene expression can lead to cataract. Intracellular delivery to hLECs, especially to sub-cellular organelles (e.g., mitochondrion and nucleus), is a key step in engineering cell...
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Main Authors: | Yexuan Guo, Tianze Xiong, Hong Yan, Rui Xue Zhang |
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Format: | Article |
Language: | English |
Published: |
Springer
2025-01-01
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Series: | Discover Nano |
Subjects: | |
Online Access: | https://doi.org/10.1186/s11671-025-04188-9 |
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