OSD1 promotes meiotic progression via APC/C inhibition and forms a regulatory network with TDM and CYCA1;2/TAM.

OSD1 promotes meiotic progression via APC/C inhibition and forms a regulatory network with TDM and CYCA1;2/TAM.

Cell cycle control is modified at meiosis compared to mitosis, because two divisions follow a single DNA replication event. Cyclin-dependent kinases (CDKs) promote progression through both meiosis and mitosis, and a central regulator of their activity is the APC/C (Anaphase Promoting Complex/Cycloso...

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Bibliographic Details
Main Authors: Laurence Cromer, Jefri Heyman, Sandra Touati, Hirofumi Harashima, Emilie Araou, Chloe Girard, Christine Horlow, Katja Wassmann, Arp Schnittger, Lieven De Veylder, Raphael Mercier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002865&type=printable
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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002865&type=printable

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