Precise stratification of prognosis in pancreatic ductal adenocarcinoma patients based on pre- and postoperative genomic information

Precise stratification of prognosis in pancreatic ductal adenocarcinoma patients based on pre- and postoperative genomic information

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) has the highest mortality rate among all cancers; hence, multidisciplinary treatment is essential for patients with PDAC. Although the resectability status, tumour marker, KRAS circulating tumour DNA (mutKRAS-ctDNA) mutations, and GATA bind...

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Main Authors: Kokichi Miyamoto, Ryuichi Yoshida, Kazuya Yasui, Kunitoshi Shigeyasu, Kazuhiro Yoshida, Tomokazu Fuji, Kosei Takagi, Yuzo Umeda, Kazuyuki Matsumoto, Yuki Fujii, Toshiaki Takahashi, Kazuya Moriwake, Masashi Kayano, Takeyoshi Nishiyama, Yasuo Nagai, Hideki Yamamoto, Hironari Kato, Hiroshi Tazawa, Mizuki Morita, Motoyuki Otsuka, Toshiyoshi Fujiwara
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Cancer Cell International
Subjects:
Pancreatic ductal adenocarcinoma
Risk stratification
Prognosis
Tumour marker
KRAS
Online Access:https://doi.org/10.1186/s12935-025-03894-9
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https://doi.org/10.1186/s12935-025-03894-9

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