Systems serology-based comparison of humoral immune responses induced by liposome or aluminum hydroxide adjuvanted SARS-CoV-2 spike protein

Systems serology-based comparison of humoral immune responses induced by liposome or aluminum hydroxide adjuvanted SARS-CoV-2 spike protein

Abstract Adjuvants play a crucial role in enhancing vaccine-induced immune responses by shaping the magnitude and quality of humoral and cellular immunity. However, the mechanism through which different adjuvants modulate effector functions is not fully understood. Here, we developed an Internationa...

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Main Authors: Soo Ji Kim, Taewoo Kim, Satyanarayana Bejjani, Mi Sun Kim, Jung Hyuk Lee, Yuna Shin, Sun-Je Woo, Beom Min Cheon, Doyoung Kim, Sumin Lee, Eunjin Cho, Junhyeon Lee, Ruchirkumar Pansuriya, Wook-Jin Park, Gaurav Pandey, Ravi Ganapathy, Jung-Ah Choi, Ju Yeon Park, Deok Ryun Kim, Cheol-Heui Yun, Jae Seung Yang, Byoung-Shik Shim, Manki Song
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Adjuvant
Aluminum hydroxide
Liposome
SARS-CoV-2
Systems serology
Online Access:https://doi.org/10.1038/s41598-025-01902-6
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https://doi.org/10.1038/s41598-025-01902-6

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