Impact of irae characteristics on efficacy of consolidative immunotherapy following chemoradiotherapy in locally advanced NSCLC

Impact of irae characteristics on efficacy of consolidative immunotherapy following chemoradiotherapy in locally advanced NSCLC

Abstract Background Consolidative PD-L1 inhibitors after concurrent chemoradiotherapy (cCRT) have become standard care in locally advanced non-small cell lung cancer (LA-NSCLC). However, the correlation between immune-related adverse event (irAE) characteristics and patient outcomes remains unclear....

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Main Authors: Xiufen Wang, Xuebing Fu, Qiaohong Liu, Juan Li, Yihui Ge, Jian Zhang, Shuyun Wang, Leirong Wang, Dahai Wang, Yanxin Sun, Yiling Gan, Haodong Sun, Zhen Wang, Yuping Sun, Aiqin Gao
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Pulmonary Medicine
Subjects:
Immune-related adverse events
Locally advanced non-small cell lung cancer
Survival
Consolidative immunotherapy
Tumor immune microenvironment
Online Access:https://doi.org/10.1186/s12890-025-03742-6
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https://doi.org/10.1186/s12890-025-03742-6

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