Advances in research on M1/M2 macrophage polarization in the pathogenesis and treatment of osteoarthritis

Osteoarthritis (OA) is a chronic inflammatory joint disease associated with aging, trauma, obesity and other pathogenic factors. It is a leading cause of pain and disability worldwide. Macrophages, the most abundant immune cells in the synovium, display significant plasticity and heterogeneity, capa...

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Bibliographic Details
Main Authors: Zhijun Deng, Wenlong Yang, Bin Zhao, Zhijun Yang, Dian Li, Fengyun Yang
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025012629
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