Intensified Upadacitinib Dosing for Adolescent Patients with Acute Severe Ulcerative Colitis

Intensified Upadacitinib Dosing for Adolescent Patients with Acute Severe Ulcerative Colitis

<b>Background/Objectives</b>: In adolescent patients with ulcerative colitis refractory to anti-tumor necrosis factor (TNF) therapy, episodes of acute severe ulcerative colitis (ASUC) require hospitalization or surgery. Upadacitinib can be a potential colectomy-sparing agent in adult ASU...

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Bibliographic Details
Main Authors: Perseus V. Patel, Martina Rigmaiden, Alka Goyal, Rachel Bensen, Dorsey Bass, Jonathan Moses, Michael J. Rosen, Ruben J. Colman
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Children
Subjects:
children
inflammatory bowel disease
targeted small-molecule therapy
janus-kinase inhibitor
pediatric
Online Access:https://www.mdpi.com/2227-9067/12/4/401
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