How to Study the Effects of Dietary Lipids on the Small Intestinal Microbiome? Methodological Design and Evaluation of the Human HealThy fAt, haPpy mIcRobiome (TAPIR) Proof-of-Concept Study

How to Study the Effects of Dietary Lipids on the Small Intestinal Microbiome? Methodological Design and Evaluation of the Human HealThy fAt, haPpy mIcRobiome (TAPIR) Proof-of-Concept Study

Background: Emerging evidence highlights the importance of the small intestinal microbiota in digestion and metabolism, underscoring the challenging need for human studies beyond fecal analyses. Objective: The TAPIR (acronym of “healthy fat, happy microbiome”) proof-of-concept study was primarily de...

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Bibliographic Details
Main Authors: Lonneke JanssenDuijghuijsen, Karen Fransen, Ruolei Deng, Corine Perenboom, Nicole de Wit, Guido Hooiveld, Mara van Trijp
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Current Developments in Nutrition
Subjects:
small intestinal microbiota
proof-of-concept human study
intestinal catheter
small intestine aspiration capsule
metabolites
mild-ketogenic diet
Online Access:http://www.sciencedirect.com/science/article/pii/S247529912500023X
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