Modulation of the gut-bone axis: Lacticaseibacillus paracasei LC86 improves bone health via anti-inflammatory metabolic pathways in zebrafish models of osteoporosis and cartilage damage

Modulation of the gut-bone axis: Lacticaseibacillus paracasei LC86 improves bone health via anti-inflammatory metabolic pathways in zebrafish models of osteoporosis and cartilage damage

AimOsteoporosis and cartilage injury are major health concerns with limited treatment options. This study investigates the therapeutic effects of Lacticaseibacillus paracasei LC86 (LC86) on osteoporosis and cartilage damage in a zebrafish (Danio rerio) model, focusing on its modulation of the gut-bo...

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Bibliographic Details
Main Authors: Yao Dong, Yukun Sun, Zhipeng Zhou, Zhonghui Gai, Yihui Cai, Mei Han, Kang Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
osteoporosis
cartilage injury
Lacticaseibacillus paracasei
gut-bone axis
zebrafish model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1493560/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1493560/full

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