DRaCOon: a novel algorithm for pathway-level differential co-expression analysis in transcriptomics

DRaCOon: a novel algorithm for pathway-level differential co-expression analysis in transcriptomics

Abstract Understanding the molecular mechanisms underlying diseases is crucial for more precise, personalized medicine. Pathway-level differential co-expression analysis, a powerful approach for transcriptomics, identifies condition-specific changes in gene-gene interaction networks, offering target...

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Bibliographic Details
Main Authors: Fernando M. Delgado-Chaves, Ferdinand Spurny, Tanja Laske, Mhaned Oubounyt, Jan Baumbach
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Bioinformatics
Subjects:
Differential networking
Pathway-level differential co-expression
Differential regulation
Disease module identification
Network-based gene expression analysis
Online Access:https://doi.org/10.1186/s12859-025-06162-9
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https://doi.org/10.1186/s12859-025-06162-9

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