CYP3A4 and CYP3A5 Genes in Cyclophosphamide-treated Chronic Lymphocytic Leukemia Patients: A Pharmacogenetics Study

Background: Approximately 75% of drug metabolism in clinical settings is attributed to cytochrome P450 enzymes. This study aimed to assess the effects of the CYP3A4*1B and CYP3A5*3 genetic variations on the clinical results of individuals with chronic lymphocytic leukemia (CLL) fo...

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Main Authors: Heba M. Elmaraghy, Menna Al-Adl, Eman R. Saifeldein, Sahar M. Elashmony, Magdy M. Youssef, Afaf El-Said, Sherif Refaat, Abdallah E. Mohammed
Format: Article
Language:English
Published: IMR Press 2025-06-01
Series:Frontiers in Bioscience-Scholar
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Online Access:https://www.imrpress.com/journal/FBS/17/2/10.31083/FBS36269
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