Coupling of mitochondrial function and skeletal muscle fiber type by a miR‐499/Fnip1/AMPK circuit

Coupling of mitochondrial function and skeletal muscle fiber type by a miR‐499/Fnip1/AMPK circuit

Abstract Upon adaption of skeletal muscle to physiological and pathophysiological stimuli, muscle fiber type and mitochondrial function are coordinately regulated. Recent studies have identified pathways involved in control of contractile proteins of oxidative‐type fibers. However, the mechanism for...

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Main Authors: Jing Liu, Xijun Liang, Danxia Zhou, Ling Lai, Liwei Xiao, Lin Liu, Tingting Fu, Yan Kong, Qian Zhou, Rick B Vega, Min‐Sheng Zhu, Daniel P Kelly, Xiang Gao, Zhenji Gan
Format: Article
Language:English
Published: Springer Nature 2016-08-01
Series:EMBO Molecular Medicine
Subjects:
contractile fiber type
gene regulation
microRNA
mitochondrial function
muscle
Online Access:https://doi.org/10.15252/emmm.201606372
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https://doi.org/10.15252/emmm.201606372

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