High throughput screening assay for the identification of ATF4 and TFEB activating compounds

Macrophages act to defend against infection but can fail to completely prevent bacterial replication and dissemination in an immunocompetent host. Recent studies have shown that activation of a host transcription factor, TFEB, a regulator of lysosomal biogenesis, could restrict intramacrophage repli...

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Bibliographic Details
Main Authors: Daniel J. Pfau, Ruslana Bryk
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Autophagy Reports
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Online Access:https://www.tandfonline.com/doi/10.1080/27694127.2025.2473765
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