Roles of LRRK2 and its orthologs in protecting against neurodegeneration and neurodevelopmental defects
In humans, variants in the LRRK2 gene are the most prevalent risk factors for Parkinson’s disease (PD). Whereas studies in model organisms have long indicated that the orthologs of the wild-type LRRK proteins protect against neurodegeneration, newer findings indicate that they also protect against n...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-04-01
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| Series: | Frontiers in Cell and Developmental Biology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2025.1569733/full |
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