DNA methylation-based prediction of response to immune checkpoint inhibition in metastatic melanoma

DNA methylation-based prediction of response to immune checkpoint inhibition in metastatic melanoma

Background Therapies based on targeting immune checkpoints have revolutionized the treatment of metastatic melanoma in recent years. Still, biomarkers predicting long-term therapy responses are lacking.Methods A novel approach of reference-free deconvolution of large-scale DNA methylation data enabl...

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Main Authors: Bastian Schilling, Sascha Tierling, Katharina Filipski, Michael Scherer, Kim N. Zeiner, Andreas Bucher, Johannes Kleemann, Philipp Jurmeister, Tabea I. Hartung, Markus Meissner, Karl H. Plate, Tim R. Fenton, Pia S. Zeiner, Patrick N. Harter
Format: Article
Language:English
Published: BMJ Publishing Group 2021-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/7/e002226.full
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https://jitc.bmj.com/content/9/7/e002226.full

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