YTHDF1-mediated m6A modification of GBP4 promotes M1 macrophage polarization in acute lung injury

YTHDF1-mediated m6A modification of GBP4 promotes M1 macrophage polarization in acute lung injury

Abstract Background Acute lung injury (ALI) is a severe condition with multifaceted causes, including inflammation and oxidative stress. This research investigates the influence of m6A (N6-methyladenosine) modification on GBP4, a protein pivotal for macrophage polarization, a critical immune respons...

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Bibliographic Details
Main Authors: Fengan Cao, Shilei Wang, Qiuyue Tan, Junna Hou, Yunlu Li, Wentao Ma, Shilong Zhao, Jing Gao
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Respiratory Research
Subjects:
m6A
ALI
Macrophage polarization
YTHDF1
GBP4
Online Access:https://doi.org/10.1186/s12931-024-03061-0
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