Activation and Expansion of Human T-Cells Using Microfluidic Devices

Activation and Expansion of Human T-Cells Using Microfluidic Devices

Treatment of cancer patients with autologous T-cells expressing a chimeric antigen receptor (CAR) is one of the most promising therapeutic modalities for hematological malignancy treatment. For this treatment, primary T-cell expansion is needed. Microfluidic technologies can be used to better unders...

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Bibliographic Details
Main Authors: Ana Belén Peñaherrera-Pazmiño, Gustavo Rosero, Dario Ruarte, Julia Pinter, Karla Vizuete, Maximiliano Perez, Marie Follo, Betiana Lerner, Roland Mertelsmann
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biosensors
Subjects:
microfluidics
suspension cells
T-cell expansion
health
Online Access:https://www.mdpi.com/2079-6374/15/5/270
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