Integrative Transcriptomic and Target Metabolite Analysis as a New Tool for Designing Metabolic Engineering in Yeast

Integrative Transcriptomic and Target Metabolite Analysis as a New Tool for Designing Metabolic Engineering in Yeast

Precision fermentation processes, especially when using edited microorganisms, demand accuracy in the bioengineering process to maximize the desired outcome and to avoid adverse effects. The selection of target sites to edit using CRISPR/Cas9 can be complex, resulting in non-controlled consequences....

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Bibliographic Details
Main Authors: Alejandro Lopez-Barbera, Nerea Abasolo, Helena Torrell, Nuria Canela, Salvador Fernández-Arroyo
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomolecules
Subjects:
CRISPR/Cas9
isoprenoids
metabolic engineering
natural products
targeted metabolite analysis
mevalonate
Online Access:https://www.mdpi.com/2218-273X/14/12/1536
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