Comprehensive review of drug resistance in mammalian cancer stem cells: implications for cancer therapy

Comprehensive review of drug resistance in mammalian cancer stem cells: implications for cancer therapy

Abstract Cancer remains a significant global challenge, and despite the numerous strategies developed to advance cancer therapy, an effective cure for metastatic cancer remains elusive. A major hurdle in treatment success is the ability of cancer cells, particularly cancer stem cells (CSCs), to resi...

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Main Authors: Bemrew Admassu Mengistu, Tirunesh Tsegaw, Yitayew Demessie, Kalkidan Getnet, Abebe Belete Bitew, Mebrie Zemene Kinde, Asnakew Mulaw Beirhun, Atsede Solomon Mebratu, Yesuneh Tefera Mekasha, Melaku Getahun Feleke, Melkie Dagnaw Fenta
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cancer Cell International
Subjects:
Cancer cells
Cancer stem cells
Drug resistance
Mammalian cancer stem cells
Online Access:https://doi.org/10.1186/s12935-024-03558-0
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https://doi.org/10.1186/s12935-024-03558-0

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