A secreted proteomic footprint for stem cell pluripotency.

A secreted proteomic footprint for stem cell pluripotency.

With a view to developing a much-needed non-invasive method for monitoring the healthy pluripotent state of human stem cells in culture, we undertook proteomic analysis of the waste medium from cultured embryonic (Man-13) and induced (Rebl.PAT) human pluripotent stem cells (hPSCs). Cells were grown...

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Main Authors: Philip A Lewis, Edina Silajdžić, Helen Smith, Nicola Bates, Christopher A Smith, Fabrizio E Mancini, David Knight, Chris Denning, Daniel R Brison, Susan J Kimber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0299365
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https://doi.org/10.1371/journal.pone.0299365

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