Luteolin prevents fMLP-induced neutrophils adhesion via suppression of LFA-1 and phosphodiesterase 4 activity

Luteolin prevents fMLP-induced neutrophils adhesion via suppression of LFA-1 and phosphodiesterase 4 activity

Luteolin is an active ingredient found early from Folium perillae and Flos lonicerae, and has a specific inhibition on phosphodiesterase 4 (PDE4) activity in vitro. Researches show luteolin has pharmacological effects of anti-inflammation, anti-anaphylaxis, antitumor, antioxidant, protection of nerv...

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Bibliographic Details
Main Authors: Dai-xun JIANG, Shu-rong LIU, Mei-hua ZHANG, Tao ZHANG, Wen-jing MA, Xiang MU, Wu CHEN
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2015-01-01
Series:Journal of Integrative Agriculture
Subjects:
luteolin
neutrophils
phosphodiesterase 4
LFA-1
MAC-1
adhesion
Online Access:http://www.sciencedirect.com/science/article/pii/S2095311914609047
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