Enhancing the Performance of Tangential Flow Microfiltration for Bioreactor Clarification

Enhancing the Performance of Tangential Flow Microfiltration for Bioreactor Clarification

Tangential flow microfiltration is easily adapted for batch and continuous bioreactor clarification. The permeate can be introduced directly to the subsequent capture step. However, the commercial use of tangential flow filtration (TFF) is limited by membrane fouling, leading to a compromised perfor...

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Bibliographic Details
Main Authors: Amir Hossein Mostafavi, Liang-Kai Chu, Xianghong Qian, John Paul Smelko, Da Zhang, Andrew Zydney, Sumith Ranil Wickramasinghe
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Membranes
Subjects:
bioreactor harvesting
clarification
continuous biomanufacturing
fouling
hydrocyclone
membrane morphology
Online Access:https://www.mdpi.com/2077-0375/15/3/78
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