SMOPCA: spatially aware dimension reduction integrating multi-omics improves the efficiency of spatial domain detection
Abstract Technological advances have enabled us to profile multiple omics layers with spatial information, significantly enhancing spatial domain detection and advancing a variety of biomedical research fields. Despite these advancements, there is a notable lack of effective methods for modeling spa...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-025-03576-9 |
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