In Vitro and In Vivo Evaluations of PLGA Microspheres Containing Nalmefene.

Poor patient compliance, untoward reactions and unstable blood drug levels after the bolus administration are impeding the pharmacotherapy for insobriety. A long-acting preparation may address these limitations. The aim of this paper was to further investigate the in vitro characteristics and in viv...

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Bibliographic Details
Main Authors: Xiangyang Xie, Wen Lin, Chuanfeng Xing, Yanfang Yang, Qiang Chi, Hui Zhang, Ying Li, Zhiping Li, Yang Yang, Zhenbo Yang, Mingyuang Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0125953
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