KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Endometrioid endometrial carcinomas (EECs) are the most common histological subtype of uterine cancer. Late-stage disease is an adverse prognosticator for EEC. The purpose of this study was to analyze EEC exome mutation data to identify late-stage-specific statistically significantly mutated genes (...

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Main Authors: Meghan L Rudd, Nancy F Hansen, Xiaolu Zhang, Mary Ellen Urick, Suiyuan Zhang, Maria J Merino, National Institutes of Health Intramural Sequencing Center Comparative Sequencing Program, James C Mullikin, Lawrence C Brody, Daphne W Bell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0251286&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0251286&type=printable

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