sumSTAAR: A flexible framework for gene-based association studies using GWAS summary statistics.

Gene-based association analysis is an effective gene-mapping tool. Many gene-based methods have been proposed recently. However, their power depends on the underlying genetic architecture, which is rarely known in complex traits, and so it is likely that a combination of such methods could serve as...

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Bibliographic Details
Main Authors: Nadezhda M Belonogova, Gulnara R Svishcheva, Anatoly V Kirichenko, Irina V Zorkoltseva, Yakov A Tsepilov, Tatiana I Axenovich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-06-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1010172&type=printable
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