Peptidomic analysis of CSF reveals new biomarker candidates for amyotrophic lateral sclerosis

Abstract Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease, and novel biomarkers are needed. We applied mass-spectrometry-based peptidomic analysis in cerebrospinal fluid (CSF) samples of ALS and non-neurodegenerative control patients (Con) from a discovery (n = 48) and...

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Bibliographic Details
Main Authors: Besnik Muqaku, Johannes Dorst, Maximilian Wiesenfarth, Markus Otto, Albert C Ludolph, Patrick Oeckl
Format: Article
Language:English
Published: Springer Nature 2025-07-01
Series:EMBO Molecular Medicine
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Online Access:https://doi.org/10.1038/s44321-025-00272-w
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