Inhibiting Ferroptosis Prevents the Progression of Steatotic Liver Disease in Obese Mice

Inhibiting Ferroptosis Prevents the Progression of Steatotic Liver Disease in Obese Mice

Ferroptosis, a form of regulated cell death characterized by lipid peroxidation and iron accumulation, has been implicated in the progression of metabolic-dysfunction-associated steatohepatitis (MASH) in obesity. This study investigated the role of ferroptosis in the development of hepatic steatosis...

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Main Authors: Gi Cheol Park, Soo-Young Bang, Ji Min Kim, Sung-Chan Shin, Yong-il Cheon, Kwang Min Kim, Hanaro Park, Eui-Suk Sung, Minhyung Lee, Jin-Choon Lee, Byung-Joo Lee
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Antioxidants
Subjects:
obesity
ferroptosis
metabolic-dysfunction-associated steatotic liver disease (MASLD)
hepatic steatosis
iron metabolism
Online Access:https://www.mdpi.com/2076-3921/13/11/1336
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https://www.mdpi.com/2076-3921/13/11/1336

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