Impaired K48-polyubiquitination downmodulates mouse norovirus propagation

Impaired K48-polyubiquitination downmodulates mouse norovirus propagation

IntroductionNoroviruses are small non-enveloped, single stranded positive-sense RNA viruses that belong to the family Caliciviridae. They are highly contagious and resistant to multiple detergents and are the infectious agents in the majority of viral gastroenteritis in adults. Due to a lack of appr...

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Bibliographic Details
Main Authors: Emmrich Wakeford, Elisabeth Werkmeister, Delphine Cayet, Sabine Poiret, Catherine Daniel, Jason Mackenzie, Jean-Claude Sirard, Frank Lafont, Ghaffar Muharram
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
norovirus
ubiquitn
innate immunity
signaling
macrophage
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1530166/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1530166/full

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