Curcumin Modulates PTPRZ1 Activity and RNA m6A Modifications in Neuroinflammation‐Associated Microglial Response

Curcumin Modulates PTPRZ1 Activity and RNA m6A Modifications in Neuroinflammation‐Associated Microglial Response

Abstract Neuroinflammation is often characterized by an overactive microglial response. Curcumin, known for its anti‐inflammatory and antioxidant properties, can mitigate microglial hyperactivity following epileptic seizures. The study delves into the molecular mechanisms underlying curcumin's...

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Bibliographic Details
Main Authors: Ninan Zhang, Ruifan Lin, Wenya Gao, Honglin Xu, Yuejia Li, Xiahe Huang, Yingchun Wang, Xianghong Jing, Wenxiang Meng, Qi Xie
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
anti‐inflammatory
curcumin
m6A post‐transcriptional modifications of RNA
microglia homeostasis
PTPRZ1
Online Access:https://doi.org/10.1002/advs.202405263
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https://doi.org/10.1002/advs.202405263

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