Optimization of a GMP-compliant automated one-pot synthesis of Al[18F]F-NOTA-Ubiquicidin29 − 41 for bacterial infection imaging by PET/CT

Optimization of a GMP-compliant automated one-pot synthesis of Al[18F]F-NOTA-Ubiquicidin29 − 41 for bacterial infection imaging by PET/CT

Abstract Background Bacterial infections and antimicrobial resistance constitute significant threats to global human health, resulting in millions of fatalities annually. The development of innovative diagnostic agents is essential to facilitate precision medicine approaches in the battle against in...

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Bibliographic Details
Main Authors: Anna Meyer, Thomas Ziegler, Jutta Moosbauer, Dirk Hellwig, Christian Fischer
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
18F radiopharmaceuticals
Aluminum[18F]fluoride
Ubiquicidin
Antimicrobial peptides
Infection imaging
Online Access:https://doi.org/10.1186/s41181-025-00370-7
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https://doi.org/10.1186/s41181-025-00370-7

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