Rituximab for refractory idiopathic membranous nephropathy: a case report of 18-month follow-up

<正>特发性膜性肾病(idiopathic membranous nephropathy,IMN)是成人最常见的难治性肾病综合征的病因之一[1],对显著的蛋白尿及肾功能恶化的高危患者均建议积极联合使用糖皮质激素及免疫抑制剂治疗,目前临床常用药物包括糖皮质激素、环磷酰胺、环孢素A或他克莫司等,但仍然有相当一部分患者对治疗缺乏反应。近年来,国外报道利妥昔单抗治疗IMN疗效显著,甚至对部分患者推荐为首选方案[2],但迄今为止,国内有关利妥昔单抗治疗...

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Bibliographic Details
Main Authors: ZHANG Yi-de, FAN Ya-ping, WANG Feng, CHEN Xiao-lan
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2019-01-01
Series:Linchuang shenzangbing zazhi
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Online Access:http://www.lcszb.com/thesisDetails?columnId=57913012&Fpath=home&index=0
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