Chemopreventive Effects of Silibinin on Colitis-Associated Tumorigenesis by Inhibiting IL-6/STAT3 Signaling Pathway

Inflammatory bowel disease (IBD), characterized by sustained inflammation, is a latent risk factor of colon tumorigenesis. Silibinin has been reported to be anti-inflammatory and antineoplastic, but its efficacy on colitis-associated cancer (CAC) has not been reported. Interlukin-6/signal transducer...

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Bibliographic Details
Main Authors: Rongjuan Zheng, Jiaheng Ma, Dan Wang, Wenxiao Dong, Sinan Wang, Tianyu Liu, Runxiang Xie, Li Liu, Bangmao Wang, Hailong Cao
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2018/1562010
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