Breaking the fortress: a mechanistic review of meningitis-causing bacteria breaching tactics in blood brain barrier

Abstract The blood-brain barrier is a physiological protective barrier around blood vessels in the brain. It prevents most bacteria and harmful substances from entering the brain through the blood. However, when bacterial meningitis occurs, bacteria enter the brain either from the circulation or by...

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Bibliographic Details
Main Authors: Yingying Quan, Yuxin Wang, Shuji Gao, Shuo Yuan, Shenao Song, Baobao Liu, Yang Wang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-025-02248-2
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