NKG2D-CAR-targeted iPSC-derived MSCs efficiently target solid tumors expressing NKG2D ligand
Summary: Mesenchymal stem cells (MSCs) hold potential in cancer therapy; however, insufficient tumor homing ability and heterogeneity limit their therapeutic benefits. Obviously, the homogeneous induced pluripotent stem cell (iPSC)-derived mesenchymal stem cells (iMSCs) with enhanced ability of tumo...
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| Main Authors: | Shuqing Tang, Yusang Zhang, Peiyun Wang, Qiyu Tang, Yating Liu, Fan Lu, Mengting Han, Miaojin Zhou, Qian Hu, Mai Feng, Desheng Liang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
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| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004225006042 |
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