Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications

Abstract Conjugation of ubiquitin to proteins (ubiquitylation) has emerged to be one of the most crucial post‐translational modifications controlling virtually all cellular processes. What was once regarded as a mere signal for protein degradation has turned out to be a major regulator of molecular...

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Bibliographic Details
Main Authors: Simone Fulda, Krishnaraj Rajalingam, Ivan Dikic
Format: Article
Language:English
Published: Springer Nature 2012-06-01
Series:EMBO Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1002/emmm.201100707
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