Computational design and evaluation of multiepitope vaccines against herpes simplex virus type 1

Computational design and evaluation of multiepitope vaccines against herpes simplex virus type 1

IntroductionHerpes simplex virus type 1 (HSV-1) is a prevalent human pathogen, causing infections in various tissues and leading to severe complications such as herpes simplex encephalitis and cognitive impairments. Despite existing antiviral treatments, recurrent infections and the lack of effectiv...

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Bibliographic Details
Main Authors: Zibo Zhao, Weixiong Wang, Jiaping Pang, Bei Zhou, Xin Li, Yifei Wang, Kai Zheng, Zhe Ren
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
HSV-1
multiepitope vaccine
molecular dynamics simulation
molecular docking
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1581571/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1581571/full

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