Increasing carotenoid production in Xanthophyllomyces dendrorhous/Phaffia rhodozyma: SREBP pathway activation and promoter engineering

Increasing carotenoid production in Xanthophyllomyces dendrorhous/Phaffia rhodozyma: SREBP pathway activation and promoter engineering

Abstract The yeast Xanthophyllomyces dendrorhous synthesizes astaxanthin, a high-value carotenoid with biotechnological relevance in the nutraceutical and aquaculture industries. However, enhancing carotenoid production through strain engineering remains an ongoing challenge. Recent studies have dem...

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Bibliographic Details
Main Authors: Alejandro Durán, Maximiliano Venegas, Salvador Barahona, Dionisia Sepúlveda, Marcelo Baeza, Víctor Cifuentes, Jennifer Alcaíno
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Biological Research
Subjects:
Astaxanthin
Gene expression regulation
Metabolic engineering
Mevalonate pathway
SREBP/Sre1 transcription factor
Promoter replacement
Online Access:https://doi.org/10.1186/s40659-024-00559-1
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https://doi.org/10.1186/s40659-024-00559-1

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