Uncovering immune cell-associated genes in breast cancer: based on summary data-based Mendelian randomized analysis and colocalization study

Uncovering immune cell-associated genes in breast cancer: based on summary data-based Mendelian randomized analysis and colocalization study

Abstract Background Breast cancer, which is the most prevalent form of cancer among women globally, encompasses various subtypes that demand distinct treatment approaches. The tumor microenvironment and immune response are of crucial significance in the development and progression of breast cancer....

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Main Authors: Jingyang Liu, Wen Sun, Ning Li, Haibin Li, Lijuan Wu, Huan Yi, Jianguang Ji, Deqiang Zheng
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Immune cell
Mendelian randomization
BulkRNA-seq
scRNA-seq
Drug target
Online Access:https://doi.org/10.1186/s13058-024-01928-0
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https://doi.org/10.1186/s13058-024-01928-0

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