The efficacy of polymyxin B in treating stroke-associated pneumonia with carbapenem-resistant Gram-negative bacteria infections: a multicenter real-world study using propensity score matching

The efficacy of polymyxin B in treating stroke-associated pneumonia with carbapenem-resistant Gram-negative bacteria infections: a multicenter real-world study using propensity score matching

ObjectivesInfection with Carbapenem-resistant Gram-negative bacteria (CR-GNB) poses further challenges in treating stroke-associated pneumonia (SAP) patients. This multicenter retrospective study aimed to evaluate the efficacy of polymyxin B (PMB) in CR-GNB-infected SAP patients and to identify fact...

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Main Authors: Hai-Hui Zhuang, Qi-Hua Chen, Wei Wang, Qiang Qu, Wei-Xin Xu, Qin Hu, Xiao-Li Wu, Ying Chen, Qing Wan, Tian-Tian Xu, Wen-Ming Long, Yue Luo, Hai-Nan Zhang, Jian Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
Subjects:
stroke-associated pneumonia
polymyxin B
carbapenem-resistant gram-negative bacteria
clinical efficacy
microbial efficacy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1413563/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1413563/full

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