Evaluation of combined BCG and SARS-CoV-2 vaccination for immune enhancement and lung protection in Syrian hamsters

Evaluation of combined BCG and SARS-CoV-2 vaccination for immune enhancement and lung protection in Syrian hamsters

Abstract SARS-CoV-2 (SCV2) has posed significant global challenges, necessitating improved immunization strategies to enhance protection and mitigate disease severity. Combining Bacille Calmette-Guérin (BCG) with SCV2 vaccine shows potential due to BCG’s immunomodulatory properties and ability to in...

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Main Authors: Abbas Ashtari, Bahar Nayeri Fasaei, Morteza Taghizadeh, Seyed Mehdi Joghataei, Mehran Dabaghian, Nader Mosavari, Mohammad Eslampanah, Ayyoob Arpanaei
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
SARS-CoV-2
Bacille Calmette-Guérin (BCG)
Syrian hamster
Vaccine
QRT-PCR
Online Access:https://doi.org/10.1038/s41598-025-04246-3
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https://doi.org/10.1038/s41598-025-04246-3

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