Impact of clinical preparation steps and use of sex-specific reference for accurate antibiotic monitoring in body fluids

Abstract Background Effective antibiotic therapy in critically ill patients requires precise dosing tailored to individual conditions. However, physiological changes in these patients can complicate drug exposure prediction, leading to treatment failure or toxicity. Therapeutic drug monitoring (TDM)...

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Bibliographic Details
Main Authors: Christian Domes, Lisa Graul, Timea Frosch, Juergen Popp, Stefan Hagel, Mathias W. Pletz, Torsten Frosch
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00823-9
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