Comparison of homologous and heterologous vaccination strategies for combating disease caused by Burkholderia pseudomallei

Comparison of homologous and heterologous vaccination strategies for combating disease caused by Burkholderia pseudomallei

IntroductionMelioidosis is a major cause of disease and mortality in endemic tropical regions, and the etiologic agent, Burkholderia pseudomallei, is being isolated increasingly from an expanded range of environmental and clinical sources in locations including the United States. The disease can hav...

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Main Authors: Sergei S. Biryukov, Christopher K. Cote, Christopher P. Klimko, Jennifer L. Dankmeyer, Nathaniel O. Rill, Melissa Hunter, Michael L. Davies, Zander M. Hedrick, Jennifer L. Shoe, Lindsey K. Schmidt, Caitlyn E. Orne, Ju Qiu, Susan L. Welkos, Mary N. Burtnick, Paul J. Brett, David DeShazer
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
melioidosis
Burkholderia pseudomallei
vaccines
heterologous
mice
protection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1596265/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1596265/full

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